Regularized Multinomial Regression for Correlated Mutations

In the Download section you can find the scripts to run RMRCM, a method to detect correlated mutations in protein sequence alignments. To do so, you first need to install R. This might be done already on your system; if not, see the R-website which provides details on how to install R. In addition to the RMRCM script, we also provide some input data, a README with a brief explanation how to run the script, and the results of an analysis of data from PFAM.